Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630
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Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 Descriptor: 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 Authors: Wang, R, Paul, D, Tong, L. Deposit date: 2016-06-22 Release date: 2016-07-13 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc.Natl.Acad.Sci.USA, 113, 2016
创建时间：
2016-06-22
