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ChIP-MS of Glucocorticoid Receptor in primary mouse macrophages

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NIAID Data Ecosystem2026-03-12 收录
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https://www.omicsdi.org/dataset/pride/PXD018077
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Glucocorticoids (GCs) are the most effective anti-inflammatory drugs in current clinical settings, yet their genomic modes of action are poorly understood. GCs bind to the Glucocorticoid Receptor (GR), which acts as a transcription factor to control gene expression in the immune system. Understanding the molecular mechanism that delineates gene repression of pro-inflammatory target genes from gene activation of metabolic genes will help to improve GC therapy and overcome adverse effects.
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2021-09-09
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