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IC50 values and relevant cytogenetic/molecular data for AML cell lines.

NIAID Data Ecosystem2026-03-07 收录

数据链接：

https://figshare.com/articles/dataset/_IC50_values_and_relevant_cytogenetic_molecular_data_for_AML_cell_lines_/769034 数据链接链接失效反馈

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资源简介：

IC50 values and relevant cytogenetic/molecular data for AML cell lines.

应用场景：

创建时间：

2013-08-09

白血病药物筛选

细胞凋亡机制

Abstract In this study, the potential antileukemic activity of grandisin, a lignan extracted from Piper solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin (0.018 t

Figshare2017-06-01 更新60

Response to dexamethasone in A549, U2OS, and Nalm6

药物转录组学

细胞系药效评估

Transcriptional profiling of A549, U2OS, and Nalm6 comparing dexamethason with vehicle control, 3 hour timepoint Two conditions (treated and untreated), three cell types. Biological replicates: 3 trea

NIAID Data Ecosystem50

Antileukemic activity of tigecycline reconstituted in saline with pyruvate and ascorbic acid.

白血病药物筛选

体外药效学

*Tigecycline solution (1 mg/mL) was preincubated at room temperature for 4 days, which was then used to determine the mean half-maximal inhibitory concentration (IC50) in OCI-AML2 and HL60 cells using

NIAID Data Ecosystem30

Caffeic acid and chlorogenic acid cytotoxicity, genotoxicity and impact on global DNA methylation in human leukemic cell lines

白血病药物筛选

甲基化调控基因

Abstract Dietary phenolic compounds such as caffeic and chlorogenic acid exert an antiproliferative effect and modulate the gene-specific DNA methylation status in human breast tumor cells, but it rem

NIAID Data Ecosystem60

Effects of PKC412 and KIN001-102, alone and combined, on MOLM14-luc+ cell cycle progression (following 24 hours of treatment) and apoptosis (following 48 hours of treatment) when cells are cultured in the presence of 50% HS-5 SCM.

白血病药物筛选

细胞周期与凋亡

Details of the assays used for these studies are provided in the Materials and Methods section.

NIAID Data Ecosystem40