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PTH regulates osteogenesis and suppresses adipogenesis through Zfp 467 in a feed-forward cyclic AMP dependent manner

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA877934
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资源简介:
Conditional deletion of the PTH1R in mesenchymal progenitors reduces osteoblast differentiation, enhances adipogenesis and increases zinc finger protein 467 (Zfp467) expression. In contrast, genetic loss of Zfp467 increased Pth1r expression and shifts mesenchymal progenitor cell fate towards osteogenesis and increased bone mass. we aims to know what is the potential downstream of zfp467 and regulates the transcription of pth1r
创建时间:
2022-09-08
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