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c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice

ChEBI2009-02-18 更新2026-07-21 收录

纤维化机制

疾病模型构建

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-13992 数据链接链接失效反馈

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资源简介：

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice

应用场景：

创建时间：

2009-02-18

纤维化机制

受体信号通路

Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanism

NIAID Data Ecosystem120

RNA-seq of fibrotic liver tissues from CCL4-induced mice. Mus musculus strain:C57/BL6

纤维化机制

RNA测序分析

To investigated the role of CD73 in liver fibrosis, RNA-sequencing of fibrotic liver tissues from CCL4-induced mice were performed. Three groups (three mice for each group) were included in this study

NIAID Data Ecosystem30

DataSheet4_Pharmacological mechanisms of Fuzheng Huayu formula for Aristolochic acid I–induced kidney fibrosis through network pharmacology.zip

纤维化机制

中药网络药理学

Renal fibrosis, characterized by the destruction of renal tubules and interstitial capillaries and the accumulation of extracellular matrix proteins, is a common outcome of chronic renal diseases and

NIAID Data Ecosystem10

Chromosomal Manipulation by Site-Specific Recombinases and Fluorescent Protein-Based Vectors

基因编辑技术

疾病模型构建

Feasibility of chromosomal manipulation in mammalian cells was first reported 15 years ago. Although this technique is useful for precise understanding of gene regulation in the chromosomal context, a

NIAID Data Ecosystem70

Table6_Network Pharmacological Analysis and Experimental Validation of the Mechanisms of Action of Si-Ni-San Against Liver Fibrosis.XLSX

纤维化机制

中药网络药理学

Background: Si-Ni-San (SNS), a commonly used traditional Chinese medicine (TCM) formula, has potency against liver diseases, such as hepatitis and non-alcoholic fatty liver disease (NAFLD). However, t

NIAID Data Ecosystem30

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile-duct-ligation in mice

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