Mitochondrial carrier homolog 2 (MTCH2) regulates the differentiation of AML cells by controlling pyruvate entry into the mitochondria, nuclear localization of pyruvate dehydrogenase complex and H3 and H4 histone acetylation
收藏NIAID Data Ecosystem2026-04-25 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP117624
下载链接
链接失效反馈官方服务:
资源简介:
Inhibiting MTCH2 or the Mitochondrial Pyruvate Carrier increased levels of pyruvate and pyruvate dehydrogenase in the nucleus leading to differentiation and loss of stemness in AML. Overall design: Gene expression analysis upon knock-down of MTCH2 by two independent shRNAs
创建时间:
2020-12-02



