Mitochondrial carrier homolog 2 (MTCH2) regulates the differentiation of AML cells by controlling pyruvate entry into the mitochondria, nuclear localization of pyruvate dehydrogenase complex and H3 and H4 histone acetylation
收藏NIAID Data Ecosystem2026-04-25 收录
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资源简介：
Inhibiting MTCH2 or the Mitochondrial Pyruvate Carrier increased levels of pyruvate and pyruvate dehydrogenase in the nucleus leading to differentiation and loss of stemness in AML. Overall design: Gene expression analysis upon knock-down of MTCH2 by two independent shRNAs
创建时间：
2020-12-02
