Case-control analysis of HLA-DRB1-DQB1 genotype from 2,555 multiple sclerosis patients and 1,365 healthy ethnically matched controls.

Only genotypes represented in at least 1% of the sample were considered. Pc = P corrected for the 28 considered genotypes. NS = not significant.Rare haplotypes belonging to the same haplogroup were grouped together: as *11 were designed *11∶01-02-03-04 -*03∶01, *11∶01-*03∶03-*05∶02 and *11∶04-*06∶03; as *07 were designed *07∶01- *02∶01 and *07∶01-*03∶03; as *13 were designed *13∶01-*06∶03-*03∶03, *13∶02-*05∶01-*05∶031-*06∶02-*06∶04-*06∶05-*06∶09, *13∶05-*03∶01 and *13∶16-*06∶04; as *04 were designed *04∶01-*03∶01-*03∶02, *04∶02-*03∶02, *04∶03– *03∶01-02-04-05, *04∶04-*03∶02-*04∶02, *04∶05-*02∶01, *04∶05-*03∶02, *04∶06-*03∶02, *04∶07-*03∶01 and *04∶08-*03∶01; as *08 were designed *08∶01-*04∶02, *08∶03-*03∶01 and *08∶04-*03∶01-*04∶02; as *01 were designed *01∶01 *05∶01, *01∶02-*05∶01 and *01∶03- *05∶01.