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CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib

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Protein Data Bank Japan2026-04-01 更新2026-04-19 收录
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CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib Descriptor: ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE Authors: Zhou, B, Gao, Y, Zhao, H, Chen, W, He, J, Zhang, T, Xiong, X. Deposit date: 2024-02-19 Release date: 2025-03-19 Last modified: 2026-04-01 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Structural Insights into Bortezomib-Induced Activation of the Caseinolytic Chaperone-Protease System in Mycobacterium tuberculosis Nat Commun, 16, 2025
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2024-02-19
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