five

Chd4

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rgd.mcw.edu2025-03-25 收录
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ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATP-dependent chromatin remodeler activity (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II; regulation of synapse assembly; terminal button organization; PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH autistic disorder (ortholog); brain disease (ortholog); breast cancer (ortholog); FOUND IN cerebellar granule cell to Purkinje cell synapse; centrosome (ortholog); chromosome, telomeric region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol

编码一种表现出ATP水解活性(同源物)的蛋白质;依赖ATP的染色质重塑酶活性(同源物);DNA结合转录因子结合(同源物);参与RNA聚合酶II转录的负调控;参与突触组装的调节;终端纽带的组织;参与CHD家族介导的染色质重塑途径;与自闭症疾病(同源物)相关;与脑部疾病(同源物)相关;与乳腺癌(同源物)相关;存在于小脑颗粒细胞至浦肯野细胞突触;中心体(同源物);染色体,端粒区域(同源物);与2,3,7,8-四氯二苯并-对-二恶英;2,6-二硝基甲苯;4,4'-磺酰二苯酚相互作用。
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