Supplementary Figures and Raw Data

Figure S1 X-tile analysis of LRFS using the X-tile program to determine the optimal cut-off values for NLR, PLR, and SII. The optimal cut-off values highlighted by black circles in the left panel are shown in the histogram of the entire cohort (right panel). (A) pre-treatment; (B) during treatment; (C) post-treatment; (D) fold changesTable S1 Optimal cut-off values for inflammatory biomarkers determined by X-tile.Raw Data:Clinical Data: Key clinical parameters relevant to ESCC management.Radiotherapy Metrics: Records of the primary gross tumor volume (GTV) to clinical target volume (CTV) margin expansion.Inflammatory Biomarkers: Pre-treatment and post-treatment values for the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII).Prognostic Outcomes: Data on local recurrence-free survival (LRFS).