The intracellular mediators of the BMP pathway SMAD1/5 bind the Imprinting Control Regions through interaction with the ZFP57/KAP1 complex and contribute to maintain their DNA methylation and H3K9me3 in mouse embryonic stem cells
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https://www.ncbi.nlm.nih.gov/sra/SRP094699
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We report that SMAD1/5 bind the ICRs by interacting with the ZFP57/KAP1 complex and that this is necessary for the proper maintenance of methylation imprints in mESCs Overall design: Examination of SMAD1/5 occupancy in Zfp57 -/- mESCs compared to the wild-type
创建时间：
2017-12-15
