ATAC-seq data from EB-HSPC after AM580 treatment compared to DMSO-treated EB

NIAID Data Ecosystem2026-03-10 收录

造血表观遗传学

染色质可及性药物响应

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP068277 数据链接链接失效反馈

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RA signalling regulated endothelial to hematopoietic transition and HSC generation. Overall design: EB-derived HSPC were profiled after 6 days of treatment with 0.2uM AM580 on OP9

创建时间：

2017-09-17

Lineage-specific transcription factors regulate DNA methylation dynamics during hematopoietic development [Methylation]. Homo sapiens

造血表观遗传学

甲基化调控基因

DNA methylation is a major epigenetic modification for gene silencing and is dramatically altered spatiotemporally during cellular development. However, the roles of DNA methylation dynamics and regul

NIAID Data Ecosystem70

Supplementary Table S5 from Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny

造血表观遗传学

TET2基因突变甲基化分析

Table S5. Table S5 provides the complete list of differentially methylated regions between TET2WT and TET2Mut HSPCs.

Figshare2026-03-04 更新40

Scalable Production of Mouse Erythroid Cells using an in vitro Embryoid Body differentiation System [ChIP-Seq]

红细胞生成

造血表观遗传学

Mouse embryonic stem (mES) cells can be manipulated ex-vivo to recapitulate the process of erythropoiesis, whereby multipotential haematopoietic stem cells undergo lineage specification, differentiati

NIAID Data Ecosystem20

Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]. Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]

造血表观遗传学

白血病机制研究

Cellular differentiation-trajectories require extensive alterations in chromatin structure and function, elicited by a diverse array of chromatin-factors (CFs). Using haematopoiesis as a model-system,

NIAID Data Ecosystem60

MOESM5 of Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

造血表观遗传学

ATAC-Seq染色质可及性分析

Additional file 5. Peak data from ATAC-Seq experiments. The presence of ATAC-Seq peaks in each cell type is indicated by a 1 (present) or 0 (not present).

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ATAC-seq data from EB-HSPC after AM580 treatment compared to DMSO-treated EB

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