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Crystal structure of M. tuberculosis InhA inhibited by SKTS1

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of M. tuberculosis InhA inhibited by SKTS1 Descriptor: 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... Authors: Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Weinrich, J.D, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. Deposit date: 2020-04-27 Release date: 2021-03-24 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.01 Å) Cite: A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. Acs Infect Dis., 7, 2021
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2020-04-27
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