Unravelling the developmental roadmap towards human brown adipose tissue
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=508659e753f2830877572885b7d77650
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资源简介：
We have developed and characterised functionally and molecularly a new chemically-defined protocol for the differentiation of human pluripotent stem cells (hPSCs) into brown adipocytes (BAs) that overcomes current limitationsThis protocol recapitulates step-by-step the physiological developmental path of human BAT.The BAs obtained expresses brown adipocyte and thermogenic markers, are insulin sensitive, and responsive to β-adrenergic stimuli.This new protocol is scalable, enabling the study of human BAs at early stages of development.
提供机构：
WT-MRC Institute of Metabolic Science
创建时间：
2022-02-20
