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Catalyst-Free Synthesis of 2,4-Disubstituted‑1<i>H</i>‑imidazoles through [3 + 2] Cyclization of Vinyl Azides with Amidines

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NIAID Data Ecosystem2026-03-10 收录
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A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent yields.

创建时间:
2017-08-30
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