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Study of Molecular and Transcriptomic Age-related Changes in the Dorsal and Ventral Areas of Hippocampus in the 5xFAD Mouse Model of Alzheimer’s Disease

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE302153
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We performed snRNA-seq of 8, 16 and 22 month old mice of 5xFAD (B6SJL/Tg) line together with control B6SJL mice to assess the changes which occur due to progression of Alzheimer's disease. Tissues of the dorsal and ventral parts of the hippocampi from 16 male animals of 8, 16 and 22 month old, respectively, were isolated to perform snRNA-seq.
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2025-07-10
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