Polycomb Repressive Complex 2 regulates basal cell fate during adult olfactory neurogenesism [scRNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE224893
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We show that Polycomb repressive complexes (PRCs) regulate lineage choice between neural and non-neural fates in the olfactory epithelium. Conditional loss of Polycomb repressive complex 2 perturbs lesion-induced neurogenesis and misexpression of lineage-specific transcription factors in multipotent olfactory globose basal cells. Single cell 3' RNAseq of olfactory epithelium from 3 Eed-KO and 3 pooled Eed-Het mice using the 10X Genomics Chromium platform and sequenced on Illumina Novaseq 6000
创建时间：
2023-12-14
