Figure 8: Disease scores of mice infected with P. aeruginosa Xen41 following peptoid or antibiotic treatment

BALB/c mice were infected with P. aeruginosa via the intratracheal route and treated with TM1, TM5, TM6, or ciprofloxacin. A modified Karnofsky score was used to score any adverse effects observed over the course of the infection. (A) Average overall Karnofsky scores for each group of mice tested from 0 hours to 72 hours, with variance represented as SD. (B) Average Karnofsky scores for each group of mice over time, split into various categories tested. Columns marked with an ‘X’ indicate where a mouse was sacrificed ahead of schedule.