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Morphodynamic atlas for Drosophila development

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DataONE2025-01-30 更新2025-04-26 收录
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This data repository contains the Drosophila morphodynamic atlas, a collection of 478 in-toto lightsheet-microscopy recordings of the Drosophila embryo at the blastoderm stage (stages 6-9). The repository comprises 18 different genotypes. For details on the data and its formating, please see \"README.md\". A table of all recordings can be found in \"MorphodynamicAtlas.csv\". A tutorial for querying and loading data from the atlas using Python can be found in \"Morphodynamic_Atlas_Tutorial.ipynb\". For details of how the atlas was created and how it can be used, please see the publication. Publication abstract: During morphogenesis, diverse cell-scale and tissue-scale processes couple to dynamically sculpt organs. In this coupling, genetic expression patterns and biochemical signals regulate and respond to mechanical deformations to ensure reproducible and robust changes in tissue geometry. A long-standing approach to characterize these interactions has been the construction of expression atla..., Dynamic atlas of early Drosophila development, collected using in-toto lightsheet microscopy and tissue cartography., Program to view multi-page .tif files, e.g. Fiji. Spreadsheet program to view list of datasets. For the Python tutorial, a working python+jupyter installation (e.g. via anaconda)., # Morphodynamic atlas of Drosophila development --- Dynamic altas of early Drosophila development created using in-toto lightsheet microscopy and tissue cartography. ## Reference Information --- ### Dataset contributors Mitchell, Noah, University of California, Santa Barbara Lefebvre, Matthew, University of California, Santa Barbara Jain-Sharma, Vishank, University of California, Santa Barbara Claussen, Nikolas, University of California, Santa Barbara Raich, Marion, Technical University Munich Gustafson, Hannah, University of California, Santa Barbara Bausch, Andreas, Technical University Munich Streichan, Sebastian, University of California, Santa Barbara ### Related manuscript The dataset presented here is described in the manuscript \"Morphodynamic Atlas for Drosophila Development\" by Mitchell et al., [https://www.biorxiv.org/content/10.1101/2022.05.26.493584v1](https://www.biorxiv.org/content/10.1101/2022.05.26.493584v1). The reader can find details about the motivation, expe...
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2025-01-30
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