Detection of transcriptome changes caused by knockdown of Ptbp1 in U251 GBM cells. Detection of transcriptome changes caused by knockdown of Ptbp1 in U251 GBM cells

We demonstrated that knocking down Ptbp1 can reprogram GBM cells into neuron-like cells. In order to further explore the mechanism of Ptbp1 causing this phenomenon, we performed mRNA sequencing on U251 cells infected with sh-Luci-3d, sh-Ptbp1-3d and sh-Ptbp1-7d. Overall design: The mRNA changes of U251 cells infected with sh-Luci-3d, sh-Ptbp1-3d and sh-Ptbp1-7d were detected.