BVD or BoCV Challenged Holstein Over Time

Animals were challenged with BVD or BoCV. Blood was collected prior to challenge, acute (4 days post challenge), maintenance (9 days post challenge), and 14 or 16 days post challenge. Serum samples were collected and small non-coding RNAs were sequencing using Illumina HiSeq 2500.

实验动物分别接受牛病毒性腹泻（BVD）或牛病毒性呼吸道疾病（BoCV）的挑战。在挑战前、急性期（挑战后4天）、维持期（挑战后9天）以及挑战后14或16天，采集了血液样本。随后，利用Illumina HiSeq 2500对血清样本中的小非编码RNA进行了测序。