We investigated the role of the transcriptional regulators Id2 and E2-2 (encoded by Tcf4) in the context of MLL-rearranged acute myeloid leukemia (AML). Using an AML mouse model driven by a Tet-off in
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth, cell proliferation, and differentiation. Myc initiates the transcription of a large cast of genes
Figure_2 - Representative images of the immunohistochemical staining reactions of GLUT1, GLUT3, HK2, PFKL, PKM2, pPDH, LDHA, MCT4 and CAIX in oral potentially malignant disorders and in oral squamous
Additional file 6: Table S5. The methylation loci and corresponding genes involved in MAPK signalling, pyruvate metabolism, glycolysis, and proteoglycan pathways.