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Crystal structure of a human HDAC8 L6 loop mutant complexed with Quisinostat

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of a human HDAC8 L6 loop mutant complexed with Quisinostat Descriptor: 2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-~{N}-oxidanyl-pyrimidine-5-carboxamide, Histone deacetylase 8, POTASSIUM ION, ... Authors: Marek, M, Shaik, T.B, Ramos-Morales, E, Romier, C. Deposit date: 2018-10-01 Release date: 2018-10-31 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.096 Å) Cite: Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
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2018-10-01
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