Codon and Composition Bias Define the Contemporary Evolution of H5N1 Influenza A (2025 Global Dataset, n = 11,602)

This dataset provides standardized genomic metrics for H5N1 influenza A virus (2025), enabling co-evolutionary analyses of: Codon usage bias (Effective Number of Codons/Nc, Codon Adaptation Index/CAI, Codon Usage Bias/CUB)Nucleotide composition (PR2 strand asymmetry, GC3 content)Mutation burden (summary statistics: mean, median, min, max)Dinucleotide frequencies (CpG, UpA)Data Sources: High-quality, near-full-length sequences (filter: ≥29,000 bp) from Nextstrain. Format: Tab-separated values (TSV) for each metric, with global summaries. Data processed and curation by [e-mail]