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DNA Methyltransferase 1 and DNA Methylation Patterning Contribute to Germinal Center B-Cell Differentiation. Homo sapiens

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NIAID Data Ecosystem2026-03-07 收录
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We performed DNA methylation (HELP) and gene expression profiling in 17 samples of purified Germinal center B cells (GCBs) and Naive B cells (NBC). We performed supervised analysis using HELP data and defined DNA methylation signature differentiting 2 subgroups of B cvells. Overall design: Study included purification of human B cells form reactive tonsils, DNA purification and DNA methylation analysis using HELP assay.

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2011-09-01
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