cFMS Tyrosine kinase in complex with 5-Cyano-furan-2-carboxylic acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3krl
下载链接
链接失效反馈官方服务：
资源简介：
cFMS Tyrosine kinase in complex with 5-Cyano-furan-2-carboxylic acid [4-(4-methyl-piperazin-1-yl)-2-piperidin-1-yl-phenyl]-amide Descriptor: 5-cyano-N-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamide, Macrophage colony-stimulating factor 1 receptor, Basic fibroblast growth factor receptor 1, ... Authors: Schubert, C. Deposit date: 2009-11-18 Release date: 2010-12-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). J.Med.Chem., 54, 2011
创建时间：
2009-11-18
