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Global miRNA expression status of human hematopoietic stem–progenitor cells modulates myelopoiesis

ChEBI2013-12-31 更新2026-07-21 收录

干细胞miRNA表达谱

谱系分化调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47519 数据链接链接失效反馈

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资源简介：

Global miRNA expression status of human hematopoietic stem–progenitor cells modulates myelopoiesis

应用场景：

创建时间：

2013-12-31

谱系分化调控

miRNA表达谱

A doxycycline-inducible system was used to induce PU.1 expression in cultured myeloid cell lines. The parent cell line used was BN (Kamath et al., Leukemia 22:1214-1225, 2008). Induction of PU.1 expre

NIAID Data Ecosystem70

An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans.

牛结核病与副结核病免疫机制

谱系分化调控

Monocyte counts are increased during human tuberculosis (TB) but it has not been determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid commitment. We demonstrated that exposur

NIAID Data Ecosystem60

An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.

基因功能研究

谱系分化调控

If deprived of wild-type p53 function, the body loses a guardian that protects against cancer. Restoration of p53 function has, therefore, been proposed as a means of counteracting oncogenesis. This c

PubMed Central1995-06-20 更新40

miRNA expression in BMSCs. miRNA expression in BMSCs

成骨软骨分化调控

干细胞miRNA表达谱

We performed microarray analysis to determine the expression profiles of miRNAs during osteoblast differentiation of BMSCs Overall design: BMSCs were cultured in osteogenic medium for 7 days. We perfo

NIAID Data Ecosystem70

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

干细胞衰老

谱系分化调控

Aged hematopoietic stem cells (HSC) display diminished self-renewal and a myeloid differentiation bias. However, the physiological drivers and molecular processes that underpin this fundamental switch

NIAID Data Ecosystem50

Global miRNA expression status of human hematopoietic stem–progenitor cells modulates myelopoiesis

资源简介：

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