Associations between IgG antibody avidity and total IgG ELISA titer.

Associations are reported between anti-MSP119 ETSR allele or anti-AMA1 3D7 allele total IgG ELISA titer readouts (Figure 1B, D) and the corresponding IgG avidity measurement by NaSCN-displacement ELISA (Figure 3E, F). Groups were assessed according to vaccination and/or parasite exposure status as outlined in Figure 3E, F. In all cases, Spearman’s rank correlation coefficient and P value are shown. n.d. = not done (too few positive responders). *Data from vaccinees receiving only a single vaccine (i.e. MSP1-only or AMA1-only) were used for this analysis.Associations between IgG antibody avidity and total IgG ELISA titer.