Analysis of X chromosome localization within the nucleus via the three-zone assay. Statistical analysis was done using Student’s t-tests. Statistically significant differences (p<0.05) are highlighted
Nucleus, chromatin, and chromosome organization studies heavily rely on fluorescence microscopy imaging to elucidate the distribution and abundance of structural and regulatory components. Three-dimen
Nuclear deformability is an essential feature of migratory cells. Intercellular movement and migration in the extracellular space requires cells to squeeze through constrictions up to an order of magn