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Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster

NIAID Data Ecosystem2026-03-13 收录

胰腺发育遗传学

增强子调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE183674 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-08-24

小细胞肺癌表观遗传学

增强子调控

Additional file 6: Table S5. Super enhancers that are co-occupied by both ASXL3 and BRD4.

Figshare2020-07-16 更新90

PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]. PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]

上皮-间质转化机制

增强子调控

We investigated the role of PHF13 in TGFβ-induced Epithelial-to-Mesenchymal Transition and found PHF13 is essential for TGFβ-promoted broadest H3K4me3 domains and super-enhancers activation. Overall d

NIAID Data Ecosystem70

Regulatory Sharing Between Estrogen Receptor α Bound Enhancers [ATAC-seq]

受体信号通路

增强子调控

The human genome encodes an order of magnitude more gene expression enhancers than promoters, suggesting that most genes are regulated by the combined action of multiple enhancers. We have previously

NIAID Data Ecosystem60

Identification of H3 Lysine 4 monomethylation Associated Proteins at Mammalian Enhancers

组蛋白修饰

增强子调控

Enhancers act to regulate cell type specific gene expression by facilitating the transcription of target genes. In mammalian cells active or primed enhancers are commonly marked by mono-methylation of

NIAID Data Ecosystem70

Basal gene expression in Daxx deficient murine pancreas

基因表达谱分析

胰腺发育遗传学

We conducted basal gene expression analysis from total pancreas isolated from six week old mice Overall design: RNA sequencing analysis was conducted in 4 (2 female and 2 male) mice per genotype

NIAID Data Ecosystem60

Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster

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