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SARS-CoV-2 3CL Protease complexed with covalent inhibitor BC671

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Protein Data Bank Japan2025-01-22 更新2026-04-04 收录
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SARS-CoV-2 3CL Protease complexed with covalent inhibitor BC671 Descriptor: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N-[(2S)-1-{[(2S)-1-hydroxy-3-(2-oxo-1,2-dihydropyridin-3-yl)propan-2-yl]amino}-4-methyl-1-oxopentan-2-yl]-1H-indole-2-carboxamide Authors: Farzandh, S, Hoffpauir, Z.A, Meneely, K.M, Lamb, A.L. Deposit date: 2024-06-26 Release date: 2025-01-15 Last modified: 2025-01-22 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents. J.Am.Chem.Soc., 147, 2025

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2024-06-26
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