Genome-wide transcriptome in the mouse seminal vesicles (SVs) and uterus (U) following neonatal DES exposure

DES is a synthetic estrogen that is associated with adverse effects on reproductive organs. Our group has employed estrogen receptor (ER) a knockout (aERKO) mice to gain insight into the contribution of ER a in DES-induced toxicity following neonatal exposure. Overall design: Mice were neonatally exposed to DES. The SVs were collected at week 5. Genome-wide transcriptome was performed by RNA-Seq.