Taf8

ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN DNA-templated transcription open complex formation (ortholog); inner cell mass cell proliferation (ortholog); maintenance of protein location in nucleus (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH infantile Refsum disease (ortholog); microcephaly (ortholog); NEURODEVELOPMENTAL DISORDER WITH SEVERE MOTOR IMPAIRMENT, ABSENT LANGUAGE, CEREBRAL HYPOMYELINATION, AND BRAIN ATROPHY (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; acrylamide; bisphenol A

编码一种表现出蛋白质异源二聚化活性（推断）；参与DNA模板转录开放复合物形成（同源）；内细胞团细胞增殖（同源）；维持蛋白质在细胞核中的定位（同源）；参与RNA聚合酶II转录起始途径；与婴儿Refsum病（同源）相关；小头畸形（同源）；伴有严重运动障碍、失语、脑白质减少和脑萎缩的神经发育障碍（同源）；存在于核质（同源）、细胞核（同源）、细胞质核周区（同源）；与4,4'-磺酰二苯酚、丙烯酰胺、双酚A相互作用。