Changes in DNaseI hypersensitivity upon ultradian (pulsed) hormone stimulation [Dnase-seq]. Mus musculus

We report changes in DNaseI accessibility genome-wide upon treatment with corticosterone (Cort) for 20 minutes, treatment with Cort for 20 minutes followed by hormone withdrawal for 40 minutes, 60 minutes continuous stimulation with Cort, as well as Mock treatments for the aforementioned conditions. Overall design: We examine DNaseI accessibility genome-wide upon following treatments: 0' Cort, 20' Cort, 60' Cort Pulsed, 60' Cort Constant, as well as Mock treatments simulating 0' Cort, 20' Cort, 60' Cort Pulsed, 60' Cort Constant.