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Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 [MGEorganoid_scRNAseq]

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE274829
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We conducted scRNAseq to investigate the transcriptomics of induced microglia (iMG) and iMG containing MGE-oriented organoids. Human embryonic stem cells-induced microglia (iMG) were transplanted to 4-week-old MGE organoids. We conducted scRNAseq to investigate the transcriptomics of 6-week-old MGE organoids with and without iMG. We also used Fluorescence-activated cell sorting (FACS) to enrich GFP-labelled iMG and condcuted scRNAseq.
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2025-09-17
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