Crystal structure of Cbl-b in complex with an allosteric inhibitor (compound 30)
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Crystal structure of Cbl-b in complex with an allosteric inhibitor (compound 30) Descriptor: 3-[3-[3-methyl-1-(4-methyl-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-1-[(1~{R})-1-(1-methylpyrazol-4-yl)ethyl]-5-(trifluoromethyl)pyridin-2-one, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... Authors: Schimpl, M. Deposit date: 2023-10-12 Release date: 2024-01-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.523 Å) Cite: Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors. J.Med.Chem., 67, 2024
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2023-10-12
