1New parameter for FM. 2Algebraic variable; see Text S1. 3Value from [26]. 4Value from [39]. 5FM not sensitive to this parameter; biologically plausible value chosen (see text). 6Fitted value; see tex
Computational modelling of biological processes poses multiple challenges in each stage of the modelling exercise. Some significant challenges include identifiability, precisely estimating parameters
Kinetic models of metabolism require detailed knowledge of kinetic parameters. However, due to measurement errors or lack of data this knowledge is often uncertain. The model of glycolysis in the para
