Leave-one-out validation for the TranNet Model.

The paired-sample T-test was used to compare the sample-wise prediction errors on real and permuted response data. This test was performed for the different numbers of top PP scoring predictors. The selected predictors corresponding to the optimal cut-off are provided with their PP scores in S1 File. The bottom rows report result using top 30% of predictors. The top rows report the results for the cancer-specific optimised set of predictors (See Fig 3 and Fig A in S1 Text).