Data are expressed as means± S.E.M. (n = 7). Water intake, food consumption are the average value of four weeks. Body weight, plasma glucose are measured at termination of administration. Control (C),
Values are shown as means ± S.E.M. (n = 13–14). *P<0.05 indicates a significant difference versus the db/+ group, #P<0.05 indicates a significant difference between db/db group and db/db+Pio group or
