TBK1 in complex with amide-coupled tetrazole analog of amlexanox
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TBK1 in complex with amide-coupled tetrazole analog of amlexanox Descriptor: 2-amino-5-oxo-7-(propan-2-yl)-N-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxamide, Serine/threonine-protein kinase TBK1 Authors: Beyett, T.S, Tesmer, J.J.G. Deposit date: 2017-11-19 Release date: 2018-09-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.598 Å) Cite: Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition. Mol. Pharmacol., 94, 2018
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2017-11-19
