Characterization of the role of SETDB1 in Muscle stem cells during skeletal muscle regeneration [ATAC-seq]

We are characterizing the rol of an H3K9 histone methyltransferase. As these proteins have the capacity to modulate chromatin, we investigate the chromatin modulation using ATAC-seq Muscle Stem Cells were isolated from the conditional mice model Setdb1-cKO and were isolated by Magnetic-activated cell sorting (MACS) and cultured in vitro Comparative gene expression profiling analysis of ATAC-seq data for muscle stem cells and muscle stem cells deleted for SETDB1