Semi-simulated TF pertubation in ATAC-seq datasets (Positive control)

Semi-simulated ATAC-seq data with TF pertubations of different pertubation strength. Pertubations in this dataset were only introduced in peaks overlapping a motif of the perturbed factor. The three .tar-files contain: 

DTFAB_sim_pos_beds.tar.gz: .bed files of the semi-simulated ATAC-seq fragments

DTFAB_sim_pos_cm.tar.gz: count matrices (per peak counts of semi-simulated fragments)

DTFAB_sim_pos_peaks.tar.gz: .bed files with ATAC-seq peak coordinates of semi-simulated fragments

The folder structure of 1.,2. & 3. is of the following format __. The original samples without any pertubation introduced are the same as in I. (pertubation strength) and only uploaded there. The original samples, for which biases & pertubations were introduced, were retrieved from ENCODE with following IDs: ENCFF495DQP, ENCFF130DND, ENCFF447ZRG, ENCFF966ELR, ENCFF358GWK, ENCFF963YZH. ChIP-seq peaks used to introduce perturbations correspond to following ENCODE identifiers: ENCFF156OCY, ENCFF592UDD, ENCFF250FJC, ENCFF500EWB.

This semi-simulated datasets is belongs to a series of datasets: 

Dataset
Description
DOI

I. pertubation strength
TF pertubation with different strengths, no biases introduced
10.5281/zenodo.10732704

II. pos control (this)
TF pertubation only introduced in (ChIP-) peaks with a motif of the respective TF.
10.5281/zenodo.10781849

III. fld
TF pertubation with additionally introduced fragment length distribution bias
10.5281/zenodo.10781109

IV. gc
TF pertubation with additionally introduced GC content bias
10.5281/zenodo.10781759