Multivariate linear regression models.

In model 1, only treatment group and the respective baseline HDL subclass composition was modelled. In model 2, BMI, baseline LDL cholesterol and the baseline ratio of triglycerides to HDL cholesterol were used as additional explanatory variables. In model 3, the change in LDL cholesterol was added as explanatory variable and the specific drug treatments were added as dummy variables.Note: for ease of interpretation, coefficients for change in LDL cholesterol are given per decrease by 20% (corresponding to approximately the change in the ezetimibe group or one half of the change in the simvastatin group or one third of the change in the combination treatment group).