The Viable-but-Nonculturable Condition Is Induced by Copper in Agrobacterium tumefaciens and Rhizobium leguminosarum

Many bacteria respond to changes in environmental conditions by entering the viable-but-nonculturable state. We have determined that copper can induce nutrient-starved Agrobacterium tumefaciens and Rhizobium leguminosarum cells to become viable but nonculturable. This is the first report of a chemical inducer of this condition.