Molecular basis for inhibition of human gamma-secretase by small molecule

Molecular basis for inhibition of human gamma-secretase by small molecule Descriptor: (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Yang, G, Zhou, R, Guo, X, Lei, J, Shi, Y. Deposit date: 2020-01-15 Release date: 2021-01-27 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of gamma-secretase inhibition and modulation by small molecule drugs. Cell, 184, 2021