The small intestine has a robust regenerative capacity, and various cell types serve as âcells-of-originâ in the epithelial regeneration process after injury. However, how much each population con
Background and Aims: Analysis of aging-induced impairments in satellite cells (SCs) â the stem cells of skeletal muscle that are required for its regeneration. Hox genes are known to control stem ce
Cohesin interacts with Mediator to link the enhancers and core promoters of actively transcribed genes bound by RNA polymerase II. Activin signaling directs human embryonic stem cells to differentiat
Tissue homeostasis requires long-term lineage fidelity of somatic stem cells. Whether and how age-related changes in somatic stem cells impact the faithful execution of lineage decisions remains large