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Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation

NIAID Data Ecosystem2026-05-10 收录

造血干细胞

化疗后骨髓恢复

数据链接：

https://data.mendeley.com/datasets/sbh6m2yw23 数据链接链接失效反馈

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资源简介：

Mendeley Data Figures and Tables for Zhang et al., 2025.

应用场景：

创建时间：

2026-01-27

造血干细胞

miRNA功能

Overexpression of miRNA, miR-24, in mouse hematopoietic progenitors increases monocytic/ granulocytic differentiation and inhibits B cell development. To determine if endogenous miR-24 is required for

NIAID Data Ecosystem80

Parallel transcriptional programs driving early-starting inheritable lineage bias of myeloid, lymphoid and dendritic cells are initiated by distinct dosage of PU.1 and IRF8 in HSCs

造血干细胞

转录调控网络

In the traditional model of hematopoiesis, blood lineages diversify from HSCs through a sequential process of hierarchical bifurcation. Each of these bifurcation nodes comprises multipotent progenitor

NIAID Data Ecosystem60

HSPCs single-cell RNA-seq, raw counts and annotation

单细胞RNA测序

造血干细胞

Raw counts and sample annotations data for a single-cell RNA-seq dataset of hematopoietic stem and progenitor cells (HSPCs) of human samples. Includes both raw counts, generated by cellranger, and cel

DataCite Commons2021-01-05 更新50

RNA-seq analysis of scat (CbyJ.Cby-Rasa3scat/Llp) and matched control mice in bone marrow and spleen

造血干细胞

基因表达分析

RASA3 (RAS p21 protein activator 3), also called GAPIII or IP4BP (inositol 1,3,4,5-tetrakisphosphate, IP4, binding protein), is a member of the GAP1 family of RAS-GTPase-activating proteins (GAPs). Th

NIAID Data Ecosystem80

Transcriptome dynamics of hematopoietic stem cell formation revealed using a combinatorial Runx1/Ly6a reporter system

造血干细胞

单细胞RNA测序

Single cell RNA-Seq time-course analysis revealed that as pre-HSCs mature into fetal liver-stage HSCs they show signs of interferon exposure, multi-lineage differentiation gene expression signatures,

干细胞与再生医学数据中心2022-02-20 更新50

Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation

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