Foxa2 programs Th2-cell mediated innate immunity in the developing lung.
收藏官方服务：
资源简介：
Foxa2 programs Th2-cell mediated innate immunity in the developing lung.
应用场景：
创建时间：
2010-03-09
相关数据集
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy. Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
Costimulation of T cells with agonist antibodies targeting 4-1BB (CD137) improves antitumor immune responses in preclinical studies, but clinical development has been hampered by on-target, off-tumor
NIAID Data Ecosystem50
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumors.. CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumors.
Here, we report the immune-mediated mechanisms underlying the improved activity of immune checkpoint blockade in glycolysis-defective tumor models. Overall design: Correlate glycolysis-related genes w
NIAID Data Ecosystem30
Acute transcriptional effects of IL-6 on murine naive CD8 T cells. Acute transcriptional effects of IL-6 on murine naive CD8 T cells
Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. To identify genes regulated by short-term IL-6 treatment, we performed RNAseq profiling of n
NIAID Data Ecosystem20
The Transcription Factor ZFfx Regulates Peripheral T Cell Self-renewal and Proliferation
Peripheral T lymphocytes share many functional properties with hematopoietic stem cells (HSCs), including long-term maintenance, quiescence, and latent proliferative potential. In addition, peripheral
NIAID Data Ecosystem50
Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1.
The expression of the protooncogenes ETS1 and ETS2 has been studied in purified human T cells activated either by cross-linking of the T-cell receptor-CD3 complex on their cell surface or by direct st
PubMed Central20
