Summary of the mechanisms of crizotinib resistance in MET NSCLC.

NIAID Data Ecosystem2026-05-02 收录

数据链接：

https://figshare.com/articles/dataset/Summary_of_the_mechanisms_of_crizotinib_resistance_in_MET_NSCLC_/25850784 数据链接链接失效反馈

官方服务：

资源简介：

Summary of the mechanisms of crizotinib resistance in MET NSCLC.

创建时间：

2024-05-17

Systems analysis of adaptive responses to MAP Kinase pathway blockade in BRAF mutant melanoma

肿瘤耐药机制

靶向药物组合

Fifty percent of cutaneous melanomas are driven by activated BRAFV600E, but tumors treated with RAF inhibitors, even when they respond dramatically, rapidly adapt and develop resistance. Thus, there i

DataONE2020-06-24 更新90

MiRNA expression data from TMZ-resistant GBM cell line

肿瘤耐药机制

miRNA表达谱

Glioblastoma multiforme(GBM) is the most common and lethal malignant primary brain tumor. Temozolomide (TMZ) is a promising chemo-therapeutic agent to treat GBM. However, resistance to TMZ develops qu

NIAID Data Ecosystem80

Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway

肿瘤耐药机制

信号通路靶向治疗

BackgroundThe sustained clinical activity of the BRAF inhibitor vemurafenib (PLX4032/RG7204) in patients with BRAFV600 mutant melanoma is limited primarily by the development of acquired resistance le

Figshare2016-01-18 更新50

Gene expression profiling in carmustine-resistant melanoma A2058 cells

肿瘤耐药机制

基因表达谱分析

Analysis of gene expression and compare the significant changed genes with associated phenotypes. Total RNA extracted from parental or carmustine-resistant A2058 cells.

NIAID Data Ecosystem80

AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition. Homo sapiens

肿瘤耐药机制

组合治疗

EGFR-mut NSCLC lines show differential suceptibility to inhibition of tankyrase in the presence of EGFR inhibitors Overall design: NSCLC cells were treated in quadruplicate with gefitinib, AZ1366 (tan

NIAID Data Ecosystem80

Summary of the mechanisms of crizotinib resistance in MET NSCLC.

资源简介：

相关数据集